Mycoplasma simbae

(Hill, 1992)

Etymology

Gr. n. mukes – fungus, Gr. neut. n. plasma – anything formed, N.L. neut. n. Mycoplasma – fungus form; Swahili. n. simba – lion, N.L. gen. n. simbae – of a lion

Taxonomy

Mycoplasmatales – Mycoplasmataceae – Mycoplasma – Mycoplasma simbae (Bovis cluster), closely related to Mycoplasma californicum (16S rRNA gene sequence similarity – 96.89%) (Fig. 1)

Type strain

LX^T (lion, UK, ≤1992), (Fig. 2, 16S rRNA gene sequence)

Genomes

one draft genome (LX^T – UK) (NCBI Genome deposit per 11/05/2024)

Cell morphology

spherical – coccoid

Colony morphology

fried egg morphology

Metabolism

oxidation of organic acids (pyruvate, lactate); non-fermentative, non-arginine-hydrolyzing, non-urea-hydrolyzing

Host

lion

Habitat

throat

Disease(s)

unknown, no disease reported

Pathogenicity

factors unknown

Epidemiology

unknown, once isolated from two zoo-kept lions

Diagnosis

cultivation and species identification by MALDI-ToF MS, serology or genetically

Fig. 1. Maximum likelihood tree showing the phylogenetic position of Mycoplasma simbae LX^T within the Bovis cluster of Mycoplasmataceae based on 16S rRNA gene sequences. The sequence of Mycoplasma synoviae WVU 1853^T was used as out-group (Synoviae cluster). Numbers at nodes represent bootstrap confidence values (1000 replications). Only values > 80% are shown. Bar, number of substitutions per nucleotide position. Credits: Joachim Spergser (Vetmeduni Vienna)

>Mycoplasma simbae LX^T

CTGGCTGTGTGCCTAATACATGCATGTCGAGCGAAGTACTTGTACTTAGCGGCGAATGGGTGAGTAACACGTACTCAACGTACCCTTCAGATTGGCATAGCGGTTGGAAACAACCGATAATACCAAATACTTGTTTAGATCGCATGATCTTTACATAAAAGACGCCTCAAAGCGTCGCTGGAGGAGCGGGGTGCGCAACATTAGCTAGTTGGTGAGGTAACGGCCCACCAAGGCAATGATGTTTAGCGGGGTTGAGAGACTGAACCGCCACACTGGGACTGAGATACGGCCCAGACTCCTACGGGAGGCAGCAGTAGGGAATATTCCACAATGGACGAAAGTCTGATGGAGCGACACAGCGTGCAGGATGAAGGCCCTATGGGTTGTAAACTGCTGTGGTAAGGGAATAAAAAATAGTATAGGAAATGATACTATATTGAATGTACCTTATTAGAAAGCAACGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGTTGCAAGCGTTATCCGGAATTATTGGGCGTAAAGCGTCTGTAGGTTGTTTATTAAGTCTGGCGTCAAATTTTGGGGCTCAACCCCAAACCGCGTTGGATACTGGTAAACTAGAGTTATGTAGAGGTTAGCGGAATTCCTTGTGAAGCGGTGAAATGCGTAGATATAAGGAAGAACACCAACATGGCGAAGGCAGCTAACTGGACATATACTGACACTGAGAGACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGTTGATCATTAGCTGATGGGGAACTCATCGGCGCAGCTAACGCATTAAATGATCCGCCTGAGTAGTACGTTCGCAAGAATAAAACTTAAAGGAATTGACGGGGACCCGCACAAGCGGTGGAGCATGTGGTTTAATTTGAAGATACGCGTAGAACCTTACCCACTCTTGACATCTTCCGCAAAGCTATAGAGATATAGTGGAGGTTAACGGAATGACAGATGGTGCATGGTTGTCGCCAGTTCGTGTCGTGAGATGTCCGGTTAAGTCCTGAAACGAGCGCAACCCCTGTCCTTAGTTACTAACATTTAGTGGAGCACTCTAAGGAGACTGCCCGACTAATCGGGAGGAAGGTGGGGACGACGTCAAATTCATCATGCCTCTTACGAGTGGGGCAACACACGTGCTACAGTGGCCGGTACACAGCGACGGACACTGGAGACAGAGCAGCAAACCACAAAAAGCCGGTCTCAGTTCGGATTGGCGTCTGCAACTCGACTCCATGAAGTCGGAATCGCTAGTAATCGTAGATCAGCTACGCTACGGTGAATACGTTCTCGGTTCTTGTACACACCGCCCGTCAAACCATGGGAGCTGGTAATGCCCGAAGTCGGTTTATAAACAAACTGCCTAAGGCAGGACTGGTGACTGGGGTTAAGTCGTAACAAGGT

Fig. 2. 16S rRNA gene sequence of Mycoplasma simbae LX^T(Accession number: NR_025964)

Species assigned by: Hill, A.C. 1992. Mycoplasma simbae sp. nov., Mycoplasma leopharyngis sp. nov., and Mycoplasma leocaptivus sp. nov., isolated from lions. Int. J. Syst. Bacteriol. 42: 518-523.