Mycoplasma primatum

(Del Giudice et al., 1971)

Etymology

Gr. n. mukes – fungus, Gr. neut. n. plasma – anything formed, N.L. neut. n. Mycoplasma – fungus form; L. n. primas – the principal (primate), L. gen. pl. n. primatum – of primates

Taxonomy

Mycoplasmatales – Mycoplasmataceae – Mycoplasma – Mycoplasma primatum (Bovis cluster), closely related to Mycoplasma bovis and Mycoplasma bovis (16S rRNA gene sequence similarity – 97.99%) (Fig. 1)

Type strain

HRC292^T (grivet monkey – Chlorocebus aethiops, USA, ≤1969), (Fig. 2, 16S rRNA gene sequence)

Genomes

one draft genome (HRC292^T – USA) (NCBI Genome deposit per 11/05/2024)

Cell morphology

spherical – coccoid – filamentous

Colony morphology

fried egg morphology (Fig. 3)

Metabolism

hydrolysis of arginine; oxidation of organic acids (pyruvate, lactate); non-fermentative; non-urea-hydrolyzing

Host

grivet monkey, once isolated from a human

Habitat

genital tract, oropharynx

Disease(s)

unknown, no disease reported

Pathogenicity

factors unknown

Epidemiology

unknown

Diagnosis

cultivation and species identification by MALDI-ToF MS, serology or genetically

Fig. 1. Maximum likelihood tree showing the phylogenetic position of Mycoplasma primatum HRC292^T within the Bovis cluster of Mycoplasmataceae based on 16S rRNA gene sequences. The sequence of Mycoplasma synoviae WVU 1853^T was used as out-group (Synoviae cluster). Numbers at nodes represent bootstrap confidence values (1000 replications). Only values > 80% are shown. Bar, number of substitutions per nucleotide position. Credits: Joachim Spergser (Vetmeduni Vienna)

>Mycoplasma primatum HRC292^T

CTGGCTGTGTGCCTAATACATGCATGTCGAGCGAAGGTAGCAATACCTTAGCGGCGAATGGGTGAGTAACACGTACTCAACGTACCTTTTAGATTGGAATAGCGGGTGGAAACATCCGATAATGCCGAATACTTATTAAGATCGCATGGTTTTAATATAAAAAGAAGCGTTTGCTTCGCTGAAAGATCGGAGTGCGCAACATTAGCTTGTTGGTGAGGTAACGGCCCACCAAGGCGATGATGTTTAGCGGGGTTGAGAGACTGAACCGCCACACTGGGACTGAGATACGGCCCAGACTCCTACGGGAGGCAGCAGTAGGGAATATTCCACAATGGACGAAAGTCTGATGGAGCGACACAGCGTGCAGGATGAAGGCCCTATGGGTTGTAAACTGCTGTGGTTAGGGAAGAAAAAGTAATATAGGAAATGATATTACCTTGACGGTACCTGATTAGAAAGCAACGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGTTGCAAGCGTTATCCGAAATTATTGGGCGTAAAGCGTCTGTAGGTTGTTTGTTAAGTCTGGCGTTAAATTTTGGGGCTCAACCCCAAAACGCGTTGGATACTGGCAAACTGGAGTTATGTAGAGGTTAGCGGAATTCCTTGTGAAGCGGTGAAATGCGTAGATATAAGGAAGAACATCAATATGGCGAAGGCAGCTAACTGGGCATACACTGACACTGAGAGACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGATGATCATTAGTTGATGGGGAACTCATCGACGCAGCTAACGCATTAAATGATCCGCCTGAGTAGTACGTTCGCAAGAATAAAACTTAAAGGAATTGACGGGGATCCGCACAAGCGGTGGAGCATGTGGTTTAATTTGAAGATACGCGTAGAACCTTACCCACTCTTGACATCTTCTGCAAAGCTATGGAGACATAGTGGAGGTTAACAGAATGACAGATGGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTCGGTTAAGTCCTGCAACGAGCGCAACCCTTGTCCTTAGTTACTAACATTTAGTTGAGCACTCTAAGGAGACTGCCCGAGTAATCGGGAGGAAGGTGGGGACGACGTCAAATCATCATGCCTCTTACGAGTGGGGCTACACACGTGCTACAATGGACGGTACAAAGAGAAGCGAAGTGGTGACATGGAGCAAACCTCAAAAAACCGTTCTCAGTTCGGATTGAAGTCTGCAACTCGACTTCATGAAGTCGGAATCGCTAGTAATCGTAGATCAGCTACGCTACGGTGAATACGTTCTCGGGTCTTGTACACACCGCCCGTCAAACCATGGGAGCTGGTAATGCCCGAAGTCGGTTTATAAAGAAACTGCCTAAGGCAGGACTGGTGACTGGGGTTAAGTCGTAACAAGGT

Fig. 2. 16S rRNA gene sequence of Mycoplasma primatum HRC292^T(Accession number: NR_025068)

Fig. 3. Colonies of Mycoplasma primatum HRC292^T on modified Hayflick’s agar after 4 days of incubation exhibiting fried egg morphology. Bar, 1 mm. Credits: Joachim Spergser (Vetmeduni Vienna)

Species assigned by: Del Giudice, R.A., Carski, T.R., Barile, M.F., Lemcke, R.M., Tully, J.G. 1971. Proposal for classifying human strain navel and related simian mycoplasmas as Mycoplasma primatum sp. n. J. Bacteriol. 108: 439-445.