Mycoplasma muris
(McGarrity et al., 1983)
Etymology
Gr. n. mukes – fungus, Gr. neut. n. plasma – anything formed, N.L. neut. n. Mycoplasma – fungus form; L. n. mus – a mouse, L. gen. n. muris – of a mouse
Taxonomy
Mycoplasmatales – Mycoplasmataceae – Mycoplasma – Mycoplasma muris (not part of a cluster), related to Mycoplasma iowae (16S rRNA gene sequence similarity – 96.54%) (Fig. 1)
Type strain
RIII-4T (mouse, USA, -1983), (Fig. 2, 16S rRNA gene sequence)
Genomes
no genome published (per 11/05/2024)
Cell morphology
spherical – coccoid
Colony morphology
fried egg morphology (Fig. 3)
Metabolism
hydrolysis of arginine; non-fermentative, non-urea-hydrolyzing; anaerobic conditions required for growth
Host
mice
Habitat
genital tract of female mice
Disease(s)
unknown, no disease reported
Pathogenicity
factors unknown
Epidemiology
unknown, has only been isolated from the vagina of 3 pregnant mice strain RIII
Diagnosis
cultivation (under strict anaerobic conditions) and species identification by MALDI-ToF MS or genetically
Fig. 1. Maximum likelihood tree showing the phylogenetic position of Mycoplasma muris RIII-4T between the Ureaplasma and Pneumoniae cluster of Mycoplasmataceae based on 16S rRNA gene sequences. Numbers at nodes represent bootstrap confidence values (1000 replications). Only values > 80% are shown. Bar, number of substitutions per nucleotide position. Credits: Joachim Spergser (Vetmeduni Vienna)
CTAGCGGGATGCCTAATACATGCAAGTCGAACGAGGTAGCAATACCTAGTGGCGAACGGGTGAGTAACACGTATCCAACATACCTATTAGTGGGGGATAACTAGATGAAAATCTAGCTAATACCGCATAGGGCATTATTATCGCATGAGAAAATGTTTAAAGTTCCGTTTGGAACGCTTTTAGATTGGGGTGCGGTGTATTAGATAGTTGGTGAGGTAATGGCTCACCAAGTCAATGATGCATAGCTGTGCTGAGAGGCAGAACAGCCACAATGGGACTGAGACACGGCCCATACTTCTACGGAAGGCAGCAGTAGGGAATTTTCCACAATGGGCGAAAGCCTGATGGAGCAATCCCGCGTGAATGATGAAGGTCTTATATAGATTGTAAAATTCTTTTATTGGAGACGAATGGTAGGAATAGGAAATGATTTCTATTTGACTGTATCCATTGAATAAGTATCGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGATGCAAGCGTTATCCGGATTTACTGGGCGTAAAGCGAGCGCGGGCGGATTTGCAAGTCTGGTGTTAAATACAACTGCTTAACGGTTGTATGCATTGGAAACTGCAAGTCTAGAGTGTAGTAGGGAGTTTTGGAACTCCATGTGGAGCGGTGGAATGCGTAGATATATGGAAGAACACCAGTGGCGAAGGCGAAAACTTAGGCTACAACTGACGCTTAGGCTCGAAAGTGTGGGGAGCAAATAGGATTAGATACCCTAGTAGTCCACACCGTAAACGATGGTAATTAAATGTTGGCACGGAATGTGTCGGTGTTGCAGTTAACACATTAAATTACCCGCCTGGGTAGTACATTCGCAAGAATGAAACTCAAACGGAATTGACGGGGACCCGCACAAGTGGTGGAGCATGTTGCTTAATTCGACAATACACGTAAAACCTTACCTAGGTTTGACATCTCCTGCAAAACTATAGAGATATAGTGGAGGTTAACAGGATGACAGGTGGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTATTGTTAGTTACTTTATCTAGCGAGACTGCCAGCGTAAGCTGGAGGAAGGTGGGGATGACGTCAAATCATCATGCCCCTTATATCTAGGGCCGCAAACGTGCTACAATGGTCGGTACAAACTGTTGCAAACCAGTAATGGGGAGCCAATCAGAGAAAGCCGATCTCAGTTCGGATTGAGGGCTGCAATTCGCCCTCATGAAGTTGGAATCACTAGTAATCGCGAATCAGACATGTCGCGGTGAATACGTTCTCGGGTCTTGTACACACCGCCCGTCAAACTATGAGAGCTGGTAATACCTAAAACCGTTAAGATAACCTCGTGAGTCTTGCGTCTAGGGTAGGACTGGTGATTGGAGTTAAGTCGTAACAAGGT
Fig. 2. 16S rRNA gene sequence of Mycoplasma muris RIII-4T (Accession number: NR_044664)
Fig. 3. Colonies of Mycoplasma muris RIII-4T on modified Hayflick’s agar after 5 days of incubation under strict anaerobic conditions exhibiting fried egg morphology. Bar, 1 mm. Credits: Joachim Spergser (Vetmeduni Vienna)