Mycoplasma lipophilum
(Del Giudice et al., 1974)
Etymology
Gr. n. mukes – fungus, Gr. neut. n. plasma – anything formed, N.L. neut. n. Mycoplasma – fungus form; Gr. n. lipos – animal fat, N.L. neut. adj. philum – loving, N.L. neut. adj. lipophilum – fat-loving
Taxonomy
Mycoplasmatales – Mycoplasmataceae – Mycoplasma – Mycoplasma lipophilum (close to the Bovis cluster), related to Mycoplasma hyopharyngis (16S rRNA gene sequence similarity – 96.42%) (Fig. 1)
Type strain
MaByT (human, USA, 1964), (Fig. 2, 16S rRNA gene sequence)
Genomes
no genome published (per 11/05/2024)
Cell morphology
spherical – coccoid
Colony morphology
fried egg morphology (Fig. 3)
Metabolism
hydrolysis of arginine; non-fermentative, non-urea-hydrolyzing
Host
human, has also been isolated from non-human primates
Habitat
upper respiratory tract
Disease(s)
unknown, no disease reported
Pathogenicity
factors unknown
Epidemiology
unknown, rarely isolated from human or non-human primates
Diagnosis
cultivation and species identification by MALDI-ToF MS, serology or genetically
Fig. 1. Maximum likelihood tree showing the phylogenetic position of Mycoplasma lipophilum MaByT close to the Bovis cluster of Mycoplasmataceae based on 16S rRNA gene sequences. The sequence of Mycoplasma synoviae WVU 1853T was used as out-group (Synoviae cluster). Numbers at nodes represent bootstrap confidence values (1000 replications). Only values > 80% are shown. Bar, number of substitutions per nucleotide position. Credits: Joachim Spergser (Vetmeduni Vienna)
CTGGCTGTGTGCCTAATACATGCATGTCGAGCGGAGTTAGCAATAACTTAGCGGCAAATGGGTGAGTAACACGTACTTAACGTACCTCTTAGTTTGACATAACGGCCGGAAACGGACGCTAATTTCAAATACTTGTGATTTTCGCATGAAGATTACATAAAAGGAGCTTCAAAGCTTCGCTGAGAGATCGGGGTGCGCAACATTAGCTAGTTGGTAAGGTAATGGCCTACCAAGGCGATGATGTTTAGCGGGGTTGAGAGACTCATCCGCCACACTGGGACTGAGATACGGCCCAGACTCCTACGGGAGGCAGCAGTAGGGAATTTTCCACAATGGACGAAAGTCTGATGGAGCGACACAGCGTGCCTGATGAAGACCTTCGGGTTGTAAAGGGCTGTGGTAAGGGAAGAAAAACTAGTATAGGAAATGATATTAGCTTGACGGTACCTTATTAGAAAGCAACGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGTTGCAAGCGTTATCCGAAATTATTGGGCGTAAAGCGTCTGTAGGTTGTTTGTTAAGTCTGACGTTAAATTTTGGGGCTCAACCCCAACTCGCGTTGGATACTGGCAAGCTAGAGTTATGTAGAGGTTAGCGGAATTCCATGTGAAGCGGTGAAATGCGTAGATATATGGAAGAACACCAAGATGGCGAAGGCAGCTAACTGGACATACACTGACACTGAGAGACGAAAGCATGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCATGCCGTAAACGATGATCATTAGTTGATGGGAGACTCATCGACGCAGCTAACGCATTAAATGATCCGCCTGAGTAGTATGCTCGCAAGAGTAAAACTTAAAGGAATTGACGGGGACCCGCACAAGCGGTGGAGCATGTGGTTTAATTTGAAGATACGCGTAGAACCTTACCCACTCTTGACATCTTCTGCAAAGCTATAGAGATATAGTAGAGGTTAACAGAATGACAGATGGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTTGGTTAAGTCCTGCAACGAGCGCAACCCTTATCCTTAGTTACTACATTTAGTTGAGGACTCTAAGGAGACTGCCCAAGTAATTGGGAGGAAGGTGGGGACGACGTCAAATCATCATGCCTCTTACGAGTGGGGCAACACACGTGCTACAATGGGCGATACAAAGAGAAGCAATATGGTGACATGGAGCAAATCTCAAAAAGTCGTTCTCAGTTCGGATTGAAGTCTGCAACTCGACTTCATGAAGTCGGAATCGCTAGTAATCGTAGATCAGCTACGCTACGGTGAATACGTTCTCGGGTCTTGTACACACCGCCCGTCACACCATGGGAGCTGGTAATGCCCGAAGTCGGTTTTTTCAAATCGCCTAAGGCAGGACTGGTGACTGGGGTTAAGTCGTAACAAGGT
Fig. 2. 16S rRNA gene sequence of Mycoplasma lipophilum MaByT (Accession number: NR_113691)
Fig. 3. Colonies of Mycoplasma lipophilum MaByT on modified Hayflick’s agar after 5 days of incubation exhibiting fried egg morphology. Bar, 1 mm. Credits: Joachim Spergser (Vetmeduni Vienna)