Mycoplasma lagogenitalium
(Kobayashi et al., 1997)
Etymology
Gr. n. mukes – fungus, Gr. neut. n. plasma – anything formed, N.L. neut. n. Mycoplasma – fungus form; Gr. n. lagos – a hare, L. gen. pl. n. genitalia – the genitals, N.L. gen. pl. n. lagogenitalium – of the genitals of a hare
Taxonomy
Mycoplasmatales – Mycoplasmataceae – Mycoplasma – Mycoplasma lagogenitalium (Hyopneumoniae cluster), closely related to Mycoplasma molare (16S rRNA gene sequence similarity – 97.20%) (Fig. 1)
Type strain
12MST (Afghan pika – Ochotona rufescens, Japan, 1990), (Fig. 2, 16S rRNA gene sequence)
Genomes
one completed genome (12MST – Japan) (NCBI Genome deposits per 11/05/2024)
Cell morphology
spherical – coccoid
Colony morphology
fried egg morphology (Fig. 3)
Metabolism
fermentation of glucose; non-arginine-hydrolyzing, non-urea-hydrolyzing
Host
Afghan pika (Ochotona rufescens)
Habitat
male genital tract (preputium)
Disease(s)
unknown, no disease reported
Pathogenicity
factors unknown
Epidemiology
unknown, once isolated from 7 male Afghan pikas of a herd in Japan
Diagnosis
cultivation and species identification by MALDI-ToF MS, serology or genetically
Fig. 1. Maximum likelihood tree showing the phylogenetic position of Mycoplasma lagogenitalium 12MST within the Hyopneumoniae cluster of Mycoplasmataceae based on 16S rRNA gene sequences. The sequence of Mycoplasma synoviae WVU 1853T was used as out-group (Synoviae cluster). Numbers at nodes represent bootstrap confidence values (1000 replications). Only values > 80% are shown. Bar, number of substitutions per nucleotide position. Credits: Joachim Spergser (Vetmeduni Vienna)
CTGGCTGTGTGCCTAATACATGCATGTTGAACGAAGCAGTGCTTGCACTGACTTAGTAGCGAATGGGTGAGTAACACGTACCTAACCTACCTTTAAGATTGGGATAACTATTGGAAACAGTAGCTAATACCAAATATGGGGTTCTTTCGCATGAAAGAGCCTTAAAAGAAGCCCTTAAAGCTTCACTTAGAAATGGGGGTGCGGAACATTAGTTAGTTGGTAGGGTAAAGGCCTACCAAGACGATGATGTTTAGCCGGGCCGAGAGGCTGTACGGCCACACTGGGACTGAGATACGGCCCAGACTCCTACGGGAGGCAGCAGTAGGGAATTTTCCACAATGAGCGAAAGCTTGATGGAGCGACACAGCGTGCAGGATGAAGGCCTTCGGGTTGTAAACTGCTGTTGCAAGGGAAGAAAAAATAAGATAGGAAATGATCTTTAATTGACGGTACCTTGTTAGAAAGCGATGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGTCGCGAGCGTTATCCGGAATTATTGGGCGTAAAGAGTTCGTAGGTTGTTTGTTAAGTCTGAAGTTAAATACTGGAGCTCAACTCCAGCCCGCTTTGGATACTGGCAAACTGGAATTGCAAAGAGGTTAGCGGAATTCCTAGTGAAGCGGTGGAATGCGTAGATATTAGGAAGAACACCAATAGGCGAAGGCAGCTAACTGGTTGTATATTGACACTGAGGAACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGATCATTAGTTGGTAGAAAAATTTACCGACGCAGCTAACGCAGTAAATGATCCGCCTGAGTAGTATGCTCGCAAGAGTGAAACTTAAAGGAATTGACGGGGACCCGCACAAGCGGAGGAGCATGTGGTTTAATTTGAAGATACGCGTAGAACCTTACCCACTCTTGACATCCCTTGCAATGCTATAGAGATATAGCGGAGGTTAACAAGGTGACAGATGGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTAGGTTAAGTCCTGCAACGAGCGCAACCCTTGTCTTTAGTTACTAATATTAAGTTAAGGACTCTAGAGAGACTGCCTGGGTAACCAGGAGGAAGGTGGGGACGACGTCAAATCATCATGCCTCTTACGAGTGGGGCAACACACGTGCTACAATGGTTGGTACAAAGAGAAGCAATATGGTGACATGGAGCAAACCTCAAAAAACCAATCTCAGTTCGGATTGAAGTCTGCAACTCGACTTCATGAAGTCGGATTCGCTAGTAATCGCAGATCAGCTACGCTGCGGTGAATACGTTCTCGGGTCTTGTACACACCGCCCGTCACACCATGGGAGTTGGTAATGCCCGAAGCCGGTTAGTTAACTTCGGAGACGACTGTCTAAGGCAGGATCGATGACTGGGGTGAAGTCGTAACAAGGT
Fig. 2. 16S rRNA gene sequence of Mycoplasma lagogenitalium 12MST (Accession number: NR_025185)
Fig. 3. Colonies of Mycoplasma lagogenitalium 12MST on modified Hayflick’s agar after 4 days of incubation exhibiting fried egg morphology. Bar, 1 mm. Credits: Joachim Spergser (Vetmeduni Vienna)