Mycoplasma haemomuris

(Neimark et al., 2002; Harasawa et al., 2015)

Etymology

Gr. n. mukes – fungus, Gr. neut. n. plasma – anything formed, N.L. neut. n. Mycoplasma – fungus form; Gr. n. haima – blood, L. n. mus – a mouse, N.L. gen. n. haemomuris – of mouse blood

Taxonomy

Mycoplasmatales – Mycoplasmataceae – Mycoplasma – Mycoplasma haemomuris (Hemoplasma cluster, Haemobartonella subcluster), related to Candidatus Mycoplasma haemohominis (16S rRNA gene sequence similarity – 91.77%), the following subspecies have been proposed: Candidatus Mycoplasma haemomuris ssp. musculi and Candidatus Mycoplasma haemomuris ssp. ratti (16S rRNA gene sequence similarity – 99.29%) (Fig. 1)

Type strain

not available, not cultivated in/on cell free media (Fig. 2, 16S rRNA gene sequences of isolate Shizuoka and S154, respectively)

Genomes

no genome published (per 11/05/2024)

Cell morphology

spherical – coccoid

Colony morphology

not cultivated on a cell-free medium

Metabolism

not assessed, probably fermentation of glucose, assimilation of glycerol; non-arginine-hydrolyzing, non-urea-hydrolyzing

Host

wild rodents (mice and rats)

Habitat

blood

Disease(s)

hemolytic anemia but often asymptomatic

Pathogenicity

factors unknown

Epidemiology

unknown

Diagnosis

PCR

Fig. 1. Maximum likelihood tree showing the phylogenetic position of Mycoplasma haemomuris (Candidatus Mycoplasma haemomuris ssp. musculi isolate Shizuoka and Candidatus Mycoplasma haemomuris ssp. ratti isolate S154) within the Hemoplasma cluster of Mycoplasmataceae based on 16S rRNA gene sequences. The sequence of Mycoplasma hyopneumoniae J^T was used as out-group (Hyopneumoniae cluster). Numbers at nodes represent bootstrap confidence values (1000 replications). Only values > 80% are shown. Bar, number of substitutions per nucleotide position. Credits: Joachim Spergser (Vetmeduni Vienna)

>Candidatus Mycoplasma haemomuris ssp. musculi isolate Shizuoka

CTGATGGCATACCTAATACATGCAAGTCGAGCGGACCTCTAGCAATAGAGGTTAGCGGCGAACGGGTGAGTAATGAATACTTAACATACCTCCATGAAGGAAATAGCTATTCGAAAGAGTAATTAATGTCCTATAGGAGCCTTCCTCACATGAGGTTGGCTTTAAAGGCGCAAGCCACTTGGAGATTGGAGTATTTTCTATTAGCTAGTTGGCGGGATAATAGCCCACCAAGGCAGTGATAGATAGCTGGTCTAAGAGGATGAACAGCCACAATGGGATTGAGATACGGCCCATATTCCTACGGGAAGCAGCAGTAGGGAATCTTCCACAATGGGCGAAAGCCTGATGGAGTGATGCCATGTGAACGATGAAGGTCTTTTTGATTGTAAAGTTCTTTTATTGGGGAAAATGATGATGGTACCCAGTGAATAAGTGACAGCAAACTATGTGCCAGCAGCTGCGGTAATACATAGGTCGCGAGCGTTATTCGGATTTATTGGGCGTAAAGCGAGCGCAGGCGGATTGGTAAGTTCTGTGTTAAATGCAGCCGCTCAACGGTTGTATGCGCAGAATACTGCCTTTCTAGAATACGGTAGAAAGTTTTGGAATTGAATGTGGAGCGGTGGAATGTGTAGATATATTCAAGAACACCAGAGGCGAAGGCGAAAACTTAGGCCGATATTGACGCTTAGGCTCGAAAGTGTGGGGAGCAAATGGGATTAGATACCCCAGTAGTCCACACCGTAAACGATGGATATTAGATGTTGGGACTTGAGTCTCAGCGTTGTAGCTTACGTGTTAAATATCCCGCCTGAGTAGTACATATGCAAATATGAAACTCAAAGGAATTGACGGGGACCTGAACAAGTGGTGGAACATGTTGCTTAATTCGACAATACACGAAAAACCTTACCAAGATTTGACATCCCCTGCGAAGCTTTAGAAATAAAGTGGAGGTTATCAGGGTGACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCATGAGATGTCTGGTTAAGTCCTGAAACGAGCGCAACCCTACTCTTTAGTTAACTTTCTAAAGAGACTGAACAGTAATGTATAGGAAGGATGGGATCACGTCAAGTCATCATGCCCCTTATATCTTGGGCCGCAAACGTGTTACAATGGTGGGTACAACGTGTCGCAAGCCAGCGATGGCAAGCCAATCACTAAAAGCCCATCCCAGTCCGGATAAAAGGCTGCAATTCGCCTTTTTGAAGTTGGAATCACTAGTAATCCCGTGTCAGCCATATCGGGGTGAATACGTTCCCAGGTCTTGTACACACCGCCCGTCAAACTATGAGAGGGAGAGGCATTCGAAAACGCATTCATTTGCGTCTAGAATGAATTTCCTGATTGGAGTTAAGTCGTAACAAGGT

>Candidatus Mycoplasma haemomuris ssp. ratti isolate S154

CTGATGGCATACCTAATACATGCAAGTCGAGCGGACCTCTAGCAATAGAGGTTAGCGGCGAACGGGTGAGTAATGAATACTTAACATACCTCCATGAAGGAAATAGCTATTCGAAAGAGTAATTAATGTCCTATAGGAGCCAGCCTCACATGAGGTTGGCTTTAAAGGCGCAAGCCACTTGGAGATTGGAGTATTTTCTATTAGCTAGTTGGCGGGATAATAGCCCACCAAGGCAGTGATAGATAGCTGGTCTAAGAGGATGAACAGCCACAATGGGATTGAGATACGGCCCATATTCCTACGGGAAGCAGCAGTAGGGAATCTTCCACAATGGGCGAAAGCCTGATGGAGTGATGCCATGTGAATGATGAAGGTCTTTTTGATTGTAAAGTTCTTTTATTGGGGAAAATGATGATGGTACCCAGTGAATAAGTGACAGCAAACTATGTGCCAGCAGCTGCGGTAATACATAGGTCGCGAGCGTTATTCGGATTTATTGGGCGTAAAGCGAGCGCAGGCGGATTGGTAAGTTCTGTGTTAAATGCAGCCGCTCAACGGTTGTATGCGCAGAATACTGCTTTTCTAGAATACGGTAGAAAGTTTTGGAATTGAATGTGGAGCGGTGGAATGTGTAGATATATTCAAGAACACCAGAGGCGAAGGCGAAAACTTAGGCCGATATTGACGCTTAGGCTCGAAAGTGTGGGGAGCAAATGGGATTAGATACCCCAGTAGTCCACACCGTAAACGATGGATATTAGATGTTGGGACTTGAGTCTCAGCGTTGTAGCTTACGTGTTAAATATCCCGCCTGAGTAGTACATATGCAAATATGAAACTCAAAGGAATTGACGGGGACCTGAACAAGTGGTGGAACATGTTGCTTAATTCGACAATACACGAAAAACCTTACCAAGATTTGACATCCCCTGCAAAGCTTTAGAAATAAAGTGGAGGTTATCAGGGTGACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCATGAGATGTCTGGTTAAGTCCTGAAACGAGCGCAACCCTACTCTTTAGTTAACTTTCTAAAGAGACTGAACAGTAATGTATAGGAAGGATGGGATCACGTCAAGTCATCATGCCCCTTATATCTTGGGCCGCAAACGTGTTACAATGGTGGGTACAACGTGTCGCAAGCCAGCGATGGCAAGCTAATCACTAAAAGCTCATCTCAGTCCGGATAAAAGGCTGCAATTCGCCTTTTTGAAGTTGGAATCACTAGTAATCCCGTGTCAGCTATATCGGGGTGAATACGTTCCCAGGTCTTGTACACACCGCCCGTCAAACTATGAGAGGGAGAGGCATTCGAAAACGTATTCATTTGCGTCTAGAATGAATTTCCTGATTGGAGTTAAGTCGTAACAAGGT

Fig. 2. 16S rRNA gene sequences of Candidatus Mycoplasma haemomuris ssp. musculi isolate Shizuoka(Accession number: AB918692) and Candidatus Mycoplasma haemomuris ssp. ratti isolate S154(Accession number: AB758439)

Species assigned by: Neimark, H., Johansson, K.E., Rikihisa, Y., Tully, J.G. 2002. Revision of haemotrophic Mycoplasma species names. Int. J. Syst. Evol. Microbiol. 52: 683; Harasawa, R., Fujita, H., Kadosaka, T., Ando, S., Rikihisa, Y. 2015. Proposal for 'Candidatus Mycoplasma subsp. musculi' in mice, and 'Candidatus Mycoplasma haemomuris subsp. ratti' in rats. Int. J. Syst. Evol. Microbiol. 65: 734-737.