Acholeplasma cavigenitalium

(Hill, 1992)

Etymology

Gr. pref. a – not, without, Gr. n. chole – bile, Gr. neut. n. plasma – anything formed, N.L. neut. n. Acholeplasma – a form for which cholesterol (a constituent of bile) is not required for growth; N.L. n. cavia – a guinea pig, L. pl. n. genitalia – the genitals, N.L. pl. gen. n. cavigenitalium – of the genitals of a guinea pig

Taxonomy

Acholeplasmatales – Acholeplasmataceae – Acholeplasma – Acholeplasma cavigenitalium, related to Acholeplasma axanthum (16S rRNA gene sequence similarity – 91.02%) (Fig. 1)

Type strain

GP3^T (guinea pig, UK, ≤1992), (Fig. 2, 16S rRNA gene sequence)

Genomes

no genomes published (per 11/05/2024)

Cell morphology

spherical – coccoid

Colony morphology

fried egg morphology

Metabolism

non-fermentative, non-arginine-hydrolyzing, non-urea-hydrolyzing, non-sterol requiring; temperature optimum for growth is 33°C

Host

guinea pig

Habitat

genital tract

Disease(s)

unknown, considered to be a commensal

Pathogenicity

factors unknown

Epidemiology

unknown, once isolated from the vaginas of several guinea pigs

Diagnosis

cultivation and species identification by MALDI-ToF MS or genetically

Fig. 1. Maximum likelihood tree showing the phylogenetic position of Acholeplasma cavigenitalium GP3^T within genus Acholeplasma based on 16S rRNA gene sequences. The sequence of Mycoplasma hyopneumoniae J^T was used as out-group (Hyopneumoniae cluster). Numbers at nodes represent bootstrap confidence values (1000 replications). Only values > 80% are shown. Bar, number of substitutions per nucleotide position. Credits: Joachim Spergser (Vetmeduni Vienna)

>Acholeplasma cavigenitalium GP3^T

CTGGCGGCGTGCCTAATACATGCAAGTCGAACGAGAGACTCCTTCGGGACGATCTAGTGGCGAACGGGTGAGTAACACGTAGGTAACCTGCCCTGTAGTTTGGAATAACCACTGGAAACGGTGGCTAATACCAAATATGAAATTTTGTGGCATCACGAAATTTTRAAAGAAGCCTTAAAGCTTTGCTACAGGAGGGGCCTGCGTCGCATTAGTTAGTTGGTAAGGTAACGGCTTACCAAGACAGTGATGCGTAGCCGGACTGAGAGGTTGAACGGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAGCAGTAGGGAATTTTCGGCAATGGGGGGAACCCTGACCGAGCGACGTCGCGTGAACGAAGAAGCACCTAGGTGCGTAAAGTTCTTTTACTAGGGAAGAATTGTTGGGATAGGAAATGATTTCAACTTGACGGTACCTTTTGAATAAGCCCCGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGGGGCAAGCGTTATCCGGAATTATTGGGCGTAAAGGGTGAGTAGGCGGTTAGTAAAGTTTAGGGTATAAGCACATTGCTTAACAATGTGAGGCTCTAAAAACTGGCTAACTAGAGTGAGACAGAGGCAAGTGGAATTCCATGTGTAGCGGTAAAATGCGTAAATATATGGAGGAACACCAGTGGCGAAGGCGGCTTGCTGGGTCTTAACTGACGCTGAGGCACGAAAGCGTGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCACGCCGTAAACGATGAGTACTAAGTGTCGGAATAATTCGGTGCTGTAGTTAACGCAATAAGTACTCCGCCTGAGTAGTACGTGCGCAAGCATGAAACTCAAAGGAATTGACGGGGACCCCGCACAAGCGGTGGATCATGTTGTTTAATTCGAAGATACGCGAAGAACCTTACCAGGTCTTGACATCCTCTGCAATGCTATAGAGATATAGCGGAGGTTACCAGAGAGACAGGTGGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTCGGTTAAGTCCGGTAACGAGCGCAACCCTTATTGCTAGTTGCCATCATTAAGTTGGGGACTCTAGCGAGACTGCCAGTGACAAACTGGAGGAAGGTGGGGATGACGTCAAATCATCATGCCCCTTATGACCTGGGCTACAAACGTGATACAATGGATAGAACAAAGGGAGGCGAAAGGGTGACCTGGAGCAAATCTCATAAAAATATTCTCAGTTCGGATTGAAGTCTGCAACTCGACTTCATGAAGCCGGAATCGCTAGTAATCGTGGATCAGAACGCCACGGTGAATACGTTCTCGGGGTTTGTACACACCGCCCGTCAAACCACGAAAGTCAGCAATACCCGAAACCGGTGGCCTAACCTTTATAGGAGGGAGCCGTCTAAGGTAGGGTTGAT

Fig. 2. 16S rRNA gene sequence of Acholeplasma cavigenitalium GP3^T(Accession number: NR_115263)

Species assigned by: Hill, A.C. 1992. Acholeplasma cavigenitalium sp. nov., isolated from the vagina of guinea pigs. Int. J. Syst. Bacteriol. 42: 589-592.