Mycoplasma fastidiosum

(Lemcke & Poland, 1980)

Etymology

Gr. n. mukes – fungus, Gr. neut. n. plasma – anything formed, N.L. neut. n. Mycoplasma – fungus form; L. neut. adj. fastidiosum – fastidious (referring to the fastidious nature of the organism)

Taxonomy

Mycoplasmatales – Mycoplasmataceae – Mycoplasma – Mycoplasma fastidiosum (not part of a cluster), closely related to Mycoplasma cavipharyngis (16S rRNA gene sequence similarity – 96.60%) (Fig. 1)

Type strain

4822^T (horse, UK, 1978), (Fig. 2, 16S rRNA gene sequence)

Genomes

one completed (4822^T– UK), one draft genome (again type strain) (NCBI Genome deposits per 11/05/2024)

Cell morphology

spherical – coccoid – filamentous (twisted)

Colony morphology

small with fried egg morphology (Fig. 3)

Metabolism

fermentation of glucose; non-arginine-hydrolyzing, non-urea-hydrolyzing

Host

horse

Habitat

nasopharynx

Disease(s)

unknown

Pathogenicity

factors unknown

Epidemiology

unknown

Diagnosis

cultivation and species identification by MALDI-ToF MS or genetically

Fig. 1. Maximum likelihood tree showing the phylogenetic position of Mycoplasma fastidiosum 4822^T in between the Pneumoniae/Ureaplasma and Hemoplasma cluster of Mycoplasmataceae based on 16S rRNA gene sequences. Numbers at nodes represent bootstrap confidence values (1000 replications). Only values > 80% are shown. Bar, number of substitutions per nucleotide position. Credits: Joachim Spergser (Vetmeduni Vienna)

>Mycoplasma fastidiosum 4822^T

CTGGCGGCATGCCTAATACATGCAAGTTGAACGAGAGTAGCAATATTCTAGTAGCGAACGGGTGAGTAACACGTATCCAACCTACCCTTATGTAAAGAATAACTAGATGAAAATCTAGCTAATACTTTATAGGAGCATTTAACATAAGTTTTTTGTTTTAAAGGCGCGTTTGCGTCGCTTAAGGATGGGGGTGCGGTGCATTAGATAGTTGGCGGGGTAATGGCCCACCAAGTCGATGATGCATAGCTGTACTGAGAGGTAGAACAGCCACAATGGGACTGAGACACGGCCCATATTCCTACGGGAAGCAGCAGTAGGGAATTTTCCACAATGGGCGAAAGCCTGATGGAGCAATGCCGCGTGAGTGATGACGGCCCTTTGGGTTGTAAAACTCTTTTATTAGGAAAAAATGAACAGAAGAGGAAATGCTTCTGTTTTGATTGTACCTTTTGAATAAGCAACGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGTTGCAAGCGTTATCCGGATTTATTGGGCGTAAAGCAAGCGCAGGTTGATTAACAAGTCTGGTGTGAAAGGCAGTAGCTTAACTATTGTTTGCATTAGAAACTGTTAATCTAGAATACAGTAGGGAGTTCTGGAATTCAATGTGGAGCGGTGAAATGCGTAGATATATTGAAGAACACCAGTGGCGAAGGCGAGAACTTGGGCTGTTATTGACGCTTAGGCTTGAAAGTGTGGGGAGCAAATAGGATTAGATACCCTAGTAGTCCACACTGTAAACGATGGATATTAGTTGTTGGGACTAGAGTCTCGGTGACGCAGCTAACGCATTAAATATCCCGCCTGGGTAGTACACTCGCAAGAGTGAAACTCAAAGGAATTGACGGGGACCTGCACAAGTGGTGGAGCATGTTGCTTAATTCGACAATACACGAAAAACCTTACCCAGGTTTGACATCCCTTGCAAAGCTATGGAAACATAGTGGAGGCTATCAAGGTGACAGGTGGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTTGGTTAAGTCCCGCAACGAGCGCAACCCCTGTCTGTAGTTAAGTATCTACAGAGACTGAAGCGAAAGCTATAGGAAGGTGGGGATGACGTCAAATCATCATGCCCCTTATGCCTGGGGCTGCAAACGTGCTACAATGGTTGGTACAAAGTGGGCGATACAGCGATGTAAAGCTTAATCACAAAAGCCAATCTCAGTTCGGATTGAAGGCTGCAACTCGCCTTCATGAAGTTGGAATCACTAGTAATCGCGTGTCAGCTATATCGCGGTGAATACGTTCTCAGGTCTTGTACACACCGCCCGTCAAACTACGAGAGGTAAGTATATCTAAAACCGCAAAATTAACCTGCAAAGTGGAATATGCGTCTAGGATAGATTTGCTGATTGGAGTTAAGTCGTAACAAGGT

Fig. 2. 16S rRNA gene sequence of Mycoplasma fastidiosum 4822^T(Accession number: NR_024987)

Fig. 3. Colonies of Mycoplasma fastidiosum 4822^T on modified Hayflick’s agar after 6 days of incubation exhibiting fried egg morphology. Bar, 1 mm. Credits: Joachim Spergser (Vetmeduni Vienna)