Mycoplasma edwardii

(Tully et al., 1970)

Etymology

Gr. n. mukes – fungus, Gr. neut. n. plasma – anything formed, N.L. neut. n. Mycoplasma – fungus form; N.L. masc. gen. n. edwardii – of Edward (referring to D.G. Edward)

Taxonomy

Mycoplasmatales – Mycoplasmataceae – Mycoplasma – Mycoplasma edwardii (Synoviae cluster), closely related to Mycoplasma canis (16S rRNA gene sequence similarity – 98.89%) (Fig. 1)

Type strain

PG24^T (dog, UK, 1951), (Fig. 2, 16S rRNA gene sequence)

Genomes

2 completed (PG24^T – UK; felid995 – Australia) (NCBI Genome deposit per 11/05/2024)

Cell morphology

spherical – coccoid

Colony morphology

fried egg morphology (Fig. 3)

Metabolism

fermentation of glucose; non-arginine-hydrolyzing, non-urea-hydrolyzing

Host

domestic dog

Habitat

upper respiratory tract, genital tract

Disease(s)

unknown, considered to be low pathogenic, occasionally associated with meningoencephalitis and polyarthritis

Pathogenicity

factors unknown

Epidemiology

worldwide occurrence in dogs; transmission by oronasal and orogenital contact

Diagnosis

cultivation and species identification by MALDI-ToF MS, serology or genetically

Fig. 1. Maximum likelihood tree showing the phylogenetic position of Mycoplasma edwardii PG24^T within the Synoviae cluster of Mycoplasmataceae based on 16S rRNA gene sequences. The sequence of Mycoplasma hyopneumoniae J^T was used as out-group (Hyopneumoniae cluster). Numbers at nodes represent bootstrap confidence values (1000 replications). Only values > 80% are shown. Bar, number of substitutions per nucleotide position. Credits: Joachim Spergser (Vetmeduni Vienna)

>Mycoplasma edwardii PG24^T

CTGGCTGTGTGCCTAATACATGCATGTCGAGCGGAGTTCTTCGGAACTTAGCGGCGAATGGGTGAGTAACACGTACTTAACATGCCTTTTAGATTGGGACAACGATGAGAAATTATCGCTAATACCGGATACTTATATGGTTCGCATGAACTATATATAAAAGGAGCTTTACGGCTTCACTAAAAGATTGGGGTGCGGAACATTAGCTAGTTGGTAAGGTAATGGCTTACCAAGGCGATGATGTTTAGCGGGGTTGAGAGACTGATCCGCCACACTGGGACTGAGATACGGCCCAGACTCCTACGGGAGGCAGCAGTAGGGAATTTTCCACAATGGACGAAAGTCTGATGGAGCGACACAGCGTGCAGGATGAAGGCCTTCGGGTTGTAAACTGCTGTTATAAGGGAAGAAAAAGCAGTAGAGGAAATGCTATTGCCTTGACGGTACCTTGTCAGAAAGCAACGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGTTGCAAGCGTTATCCGGAATTATTGGGCGTAAAGCGTCTGTAGGTTGTTTGTTAAGTCTGGCGTGAAAACTTGGGGCTCAACCCCAAATTGCGTTGGATACTGGCAAGCTAGAATTGTGTAGAGGTTAGCGGAATTCCTAGTGAAGCGGTGAAATGCGTAGATATTAGGAAGAACACCAACATGGCGAAGGCAGCTAACTGGGCACATATTGACACTGAGAGACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCTGTAAACGATGATGATTAGCTGATAGAAAACTATCGGCGCAGCTAACGCATTAAATCATCCGCCTGAGTAGTATGCTCGCAAGAGTGAAACTTAAAGGAATTGACGGGGATCCGCACAAGCGGTGGAGCATGTGGTTTAATTTGAAGATACGCGTAGAACCTTACCCACTCTTGACATCTTCCGCAAAGCTATAGAGATATAGTGGAGGCTAACGGAATGACAGATGGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTCGGTTAAGTCCTGCAACGAGCGCAACCCTTGTCCTTAGTTAATTTTCTAGGGAGACTGCCCGAGTAATTGGGAGGAAGGTGGGGACGACGTCAAATCATCATGCCTCTTACGAGTGGGGCAACACACGTGCTACAATGGACGGTACAAAGAGAAGCAAGACGGCGACGTGGAGCAAATCTCAAAAAACCGTTCTCAGTTCGGATTGTAGTCTGCAACTCGACTACATGAAGTCGGAATCGCTAGTAATCGTAGATCAGCTACGCTACGGTGAATACGTTCTCGGGTCTTGTACACACCGCCCGTCACACCATGGGAGCTGGTAATGCCCGAAGTCGGTTTTGTTAACTACGGAGACAACTGCCTAAGGCAGGGCCGGTGACTGGGGTGAAGTCGTAACAAGGT

Fig. 2. 16S rRNA gene sequence of Mycoplasma edwardii PG24^T(Accession number: NR_104953)

Fig. 3. Colonies of Mycoplasma edwardii PG24^T on modified Hayflick’s agar after 4 days of incubation exhibiting fried egg morphology. Bar, 1 mm. Credits: Joachim Spergser (Vetmeduni Vienna)

Species assigned by: Tully, J.G., Barile, M.F., Del Giudice, R.A., Carski, T.R., Armstrong, D., Razin, S. 1970. Proposal for classifying strain PG-24 and related canine mycoplasmas as Mycoplasma edwardii sp. n. J. Bacteriol. 101: 346-349.