Mycoplasma caviae
(Hill, 1971)
Etymology
Gr. n. mukes – fungus, Gr. neut. n. plasma – anything formed, N.L. neut. n. Mycoplasma – fungus form; N.L. n. cavia – a guinea pig, N.L. gen. n. caviae – of a guinea pig
Taxonomy
Mycoplasmatales – Mycoplasmataceae – Mycoplasma – Mycoplasma caviae (Bovis cluster), closely related to Mycoplasma fermentans (16S rRNA gene sequence similarity – 99.38%) (Fig. 1)
Type strain
G122T (guinea pig, UK, ≤1971), (Fig. 2, 16S rRNA gene sequence)
Genomes
one completed (G122T – UK); one draft genome (again type strain) (NCBI Genome deposit per 11/05/2024)
Cell morphology
spherical – coccoid
Colony morphology
fried egg morphology (Fig. 3)
Metabolism
fermentation of glucose and hydrolysis of arginine; non-urea-hydrolyzing
Host
guinea pig
Habitat
oropharynx, respiratory tract
Disease(s)
unkown
Pathogenicity
factors unknown
Epidemiology
unknown
Diagnosis
cultivation and species identification by MALDI-ToF MS, serology or genetically
Fig. 1. Maximum likelihood tree showing the phylogenetic position of Mycoplasma caviae G122T within the Bovis cluster of Mycoplasmataceae based on 16S rRNA gene sequences. The sequence of Mycoplasma synoviae WVU 1853T was used as out-group (Synoviae cluster). Numbers at nodes represent bootstrap confidence values (1000 replications). Only values > 80% are shown. Bar, number of substitutions per nucleotide position. Credits: Joachim Spergser (Vetmeduni Vienna)
CTGGCTGTGTGCCTAATACATGCATGTCGAGCGAAGGTAGCAATACCTTAGCGGCGAATGGGTGAGTAACACGTGCTCAACGTACCCTTCAGTTTGGCATAGCGACTGGAAACAGTCGATAATTCCAAATACTCGTAATTTTCGCATGAAGATTACGTAAAAGAAGCGTTTGCTTCGCTGGAGGATCGGGGTGCGTAACATTAGCTAGTTGGTGAGGTAACGGCCCACCAAGGCGATGATGTTTAGCGGGGTTGAGAGACTGAACCGCCACACTGGGACTGAGATACGGCCCAGACTCCTACGGGAGGCAGCAGTAGGGAATATTCCACAATGGGCGAAAGCCTGATGGAGCGACACAGCGTGAAGGATGAAGGTCCTATGGATTGTAAACTTCTGTGGTGAGGGAAGAAAAGACAGAATAGGAAATGATTTTGTTTTGACGGTACCTTATTAGAAAGCAACGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGTTGCAAGCGTTATCCGGAATTATTGGGCGTAAAGCGTCTGTAGGTTGTTTGTTAAGTCTGGCGTTAAATTTTGGGGCTCAACCCCAAAACGCGTTGGATACTGGCAGACTAGAGTTGTGTAGAGGTTAGCGGAATTCCTTGTGAAGCGGTGAAATGCGTAGATATAAGGAAGAACACCAATATGGCGAAGGCAGCTAACTGGACATATACTGACACTGAGAGACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGATGATCATTAGCTGATGGGGAACTCATCGGCGCAGCTAACGCATTAAATGATCCGCCTGAGTAGTACGTTCGCAAGAATAAAACTTAAAGGAATTGACGGGGATCCGCACAAGCGGTGGAGCATGTGGTTTAATTTGAAGATACGCGTAGAACCTTACCCACTCTTGACATCTTCTGCAAAGCTATGGAGACATAGTGGAGGTTAACAGAATGACAGATGGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTCGGTTAAGTCCTGCAACGAGCGCAACCCTTATCCTTAGTTACTACCATTTAGTTGAGGACTCTAAGGAGACTGCCCGAGTAATCGGGAGGAAGGTGGGGATGACGTCAAATCATCATGCCTCTTACGAGTGGGGCAACACACGTGCTACAATGGCCGGTACAAAGAGAAGCGAAGTGGTGACATGGAGCAAACCTCAAAAAACCGGTCTCAGTTCGGATTGTAGTCTGCAACTCGACTACATGAAGTCGGAATCGCTAGTAATCGTAGATCAGCTACGCTACGGTGAATACGTTCTCGGGTCTTGTACACACCGCCCGTCAAACCATGGGAGCTGGTAATGCCCGAAGTCGGTTTATAAACAAACTGCCTAAGGCAGGACTGGTGACTGGGGTTAAGTCGTAACAAGGT
Fig. 2. 16S rRNA gene sequence of Mycoplasma caviae G122T (Accession number: NR_025061)
Fig. 3. Colonies of Mycoplasma caviae G122T on modified Hayflick’s agar after 4 days of incubation exhibiting fried egg morphology. Bar, 1 mm. Credits: Joachim Spergser (Vetmeduni Vienna)