Mycoplasma ovis

(Neitz et al., 1934; Neimark et al., 2004)

Etymology

Gr. n. mukes – fungus, Gr. neut. n. plasma – anything formed, N.L. neut. n. Mycoplasma – fungus form; L. n. ovis – a sheep, L. gen. n. ovis – of a sheep

Taxonomy

Mycoplasmatales – Mycoplasmataceae – Mycoplasma – Mycoplasma ovis (Haemoplasma cluster, Eperythrozoon subcluster), closely related to Candidatus Mycoplasma haemovis and Candidatus Mycoplasma haemocervae (16S rRNA gene sequence similarities – 98.65 and 98.36%, respectively) (Fig. 1)

Type strain

not available, not cultivated in/on cell free media (Fig. 2, 16S rRNA gene sequence of isolate Michigan)

Genomes

one completed (isolate Michigan – USA) (NCBI Genome deposit per 11/05/2024)

Cell morphology

spherical – coccoid

Colony morphology

not cultured on cell free medium

Metabolism

glucose fermentation; assimilation of glycerol; non-arginine-hydrolyzing, non-urea-hydrolyzing

Host

sheep, goats, deer, reindeer

Habitat

blood

Disease(s)

hemolytic anemia, often asymptomatic

Pathogenicity

factors unknown

Epidemiology

worldwide occurrence; transmission via blood-feeding arthropod vectors

Diagnosis

PCR

Fig. 1. Maximum likelihood tree showing the phylogenetic position of Mycoplasma ovis isolate Michigan within the Hemoplasma cluster of Mycoplasmataceae based on 16S rRNA gene sequences. The sequence of Mycoplasma hyopneumoniae J^Twas used as out-group (Hyopneumoniae cluster). Numbers at nodes represent bootstrap confidence values (1000 replications). Only values > 80% are shown. Bar, number of substitutions per nucleotide position. Credits: Joachim Spergser (Vetmeduni Vienna)

>Mycoplasma ovis isolate Michigan

CTGGTGGTATGCATAACACATGCAAGTCGAACGAGTAGAACTTGTTCTGCTAGTGGCAAACGGGCGAGTAATACATATTTAACTTACTTCCGCGAGTAGGATAGCAGCCCGAAAGGGCTATTAATACTACATAGGTTTATGGACTTGTAAATTAAAGGAGGCGCCCTCGGGAGCCTCGCGCGGAAAAGGGAATATGTCCTATTAGGTAGTTGGCGGGGTAAAGGCCCACCAAGCCAATGATGGGTAGCTGGACTGAGAGGTTGAACAGCCGCAATGGGATTGAGATATGGCCCATATTCCTACGGGAAGCAGCAGTGAGGAATTTTTCACAATGGACGAAAGTCTGATGGAGCAATACCACGTGAACGATGAAGGTCTTCTGATTGTAAAGTTCTTTTATTTAGGAAAAAAAGCGCGCTAGGAAATGAGCGCGCCTTGATGGTACTAATTGAATAAGTGACAGCTAACTATGTGCCAGCAGCTGCGGTAAAACATAGGTCACAAGCATTATCCGGATTTATTGGGCGTAAAGGAAGCGTAGGCGGGGAGGCTGATCCATTGTTAAAGGCATTTGCTCAACAAATGTGTGCGATGGAGATCTCCTCCTTAGAGTTAATCAAGGGGTACTGGAATTCAATGTGTAGCGGTGGAATGCGTAGATATATTGAGGAAAACCAGAGGCTAAGGCGAGTACCTGGGATATAACTGACGCTGAGGCTTGAAAGCGTGGGGAGCAAATGGGATTAGATACCCCAGTAGTCCACGCCGTAAACGATGAGCATTAGGTATTTGATGTTAGGTCGAGTGCTGTAGCTAACGCGTTAAATGCTCCGCCTGGGTAGTATATATGCAAATATGAAACTCAAAGAAATTGACGGGGACCTGAACAAGTGGTGGAGCATGTTGCTTAATTCGATAATACACGAAAAACCTTACCAAGGCTTGTTATCTACTGCAAAACTATAGAAATATGGTGGAGTATATCAGTAAGACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCTTGAGATGTTTGGTTAAGTCCCGTAACGAGCGCAACCCTACTCTCTAGTTAATTAGTTCTAGAGTGACTGAATCGTAAGATATAGGAAGGATGGGGCCAAGTCAAGTCATCATGCCCCTTATGCCTTGGGTTGCAAACGTGCTACAATGGTAGGTACAATGTGTTGCAATCTAGCGATAGTGAGCTAATCACCGAAAACCTATCTCAGTCCGGATAAAAGGCTGCAATTCGCCTATTTGAAGTTGGAATCACTAGTAATCCTGTGTCAGCTATATCAGGGTGAATACGTTCCCAGGTCTTGTACACACCGCCCGTCAAACTATGAAAGAAAGTATCAGTCAAAACCGCATTCAATTGTGTCTAGATTGGTAATTTTGATTGGAGTTAAGTCGTAACAAGGT

Fig. 2. 16S rRNA gene sequence of Mycoplasma ovis isolate Michigan (Accession number: CP006935)

Species assigned by: Neitz, W.O., Alexander, R.A., Du Toit, P.J. 1934. Eperythrozoon ovis (sp. nov.). Infection in sheep. Onderstepoort Journal of Veterinary Science 3: 263-274; Neimark, H., Hoff, B., Ganter, M. 2004. Mycoplasma ovis comb. nov. (formerly Eperythrozoon ovis), an epierythrocytic agent of haemolytic anaemia in sheep and goats. Int. J. Syst. Evol. Microbiol. 54: 365-371.